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TSHR (aa101-115) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - TSHR (aa101-115) Antibody (internal region) AF3630a
    AF3630a (0.5 µg/ml) staining of Human Thyroid gland lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16473
Other Accession NP_000360.2, NP_001018046.1, 7253
Reactivity Human
Predicted Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 86830 Da
Additional Information
Gene ID 7253
Other Names Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R, TSHR, LGR3
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTSHR (aa101-115) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms LGR3
Function Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in the thyroid.
Research Areas
Citations (0)

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This antibody is expected to recognize reported isoform 1 (NP_000360.2) and isoform 2 (NP_001018046.1). The immunizing peptide sequence corresponds to a part of the extracellular domain.


Subclinical nonautoimmune hyperthyroidism in a family segregates with a thyrotropin receptor mutation with weakly increased
constitutive activity. Nishihara E, Chen CR, Higashiyama T, Mizutori-Sasai Y, Ito M, Kubota S, Amino N, Miyauchi A, Rapoport B. Thyroid. 2010 Nov;20(11):1307-14. PMID: 20929407

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$ 325.00
Cat# AF3630a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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