|Application ||WB, IHC, E|
|Other Accession||NP_006163.1, 4878, 230899 (mouse), 24602 (rat)|
|Reactivity||Human, Mouse, Rat|
|Predicted||Pig, Dog, Cow|
|Calculated MW||16708 Da|
|Other Names||Natriuretic peptides A, CDD-ANF, Cardiodilatin, CDD, Cardiodilatin-related peptide, CDP, Prepronatriodilatin, Atrial natriuretic factor, ANF, Atrial natriuretic peptide, ANP, NPPA, ANP, PND|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Atrial natriuretic factor Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The immunizing peptide represents aa137-150 of the precursor NPPA.
Decompensated heart failure is associated with reduced corin levels and decreased cleavage of pro-atrial natriuretic peptide. Ibebuogu UN, Gladysheva IP, Houng AK, Reed GL. Circ Heart Fail. 2011 Mar 1;4(2):114-20. PMID: 21216831
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