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CACNB2 (aa565-579) Antibody (C-Term)

Peptide-affinity purified goat antibody

     
  • WB - CACNB2 (aa565-579) Antibody (C-Term) AF3651a
    AF3651a (1 µg/ml) staining of Jurkat lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q08289
Other Accession NP_000715.2, NP_963890.2, NP_963884.2, NP_963891.1, NP_963887.2, NP_963865.2, NP_963864.1, NP_963866.2, NP_001161417.1, 783, 12296 (mouse), 116600 (rat)
Reactivity Human, Mouse
Predicted Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 73581 Da
Additional Information
Gene ID 783
Other Names Voltage-dependent L-type calcium channel subunit beta-2, CAB2, Calcium channel voltage-dependent subunit beta 2, Lambert-Eaton myasthenic syndrome antigen B, MYSB, CACNB2, CACNLB2, MYSB
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCACNB2 (aa565-579) Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CACNB2
Synonyms CACNLB2, MYSB
Function The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Cellular Location Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side
Tissue Location Expressed in all tissues.
Research Areas
Citations (0)

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Background

This antibody is expected to recognize all reported isoforms (NP_000715.2; NP_963890.2; NP_963884.2; NP_963891.1; NP_963887.2; NP_963865.2; NP_963864.1; NP_963866.2; NP_001161417.1).

References

Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes Burashnikov E, Pfeiffer R, Barajas-Martinez H, Delpón E, Hu D, Desai M, Borggrefe M, Häissaguerre M, Kanter R, Pollevick GD, Guerchicoff A, Laiño R, Marieb M, Nademanee K, Nam GB, Robles R, Schimpf R, Stapleton DD, Viskin S, Winters S, Wolpert C, Zimmern Heart Rhythm. 2010 Dec;7(12):1872-82. PMID: 20817017

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$ 335.00
Cat# AF3651a
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