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Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P20020 |
| Other Accession | NP_001001323.1, NP_001673.2, 490, 67972 (mouse), 29598 (rat) |
| Reactivity | Human |
| Predicted | Mouse, Rat, Pig, Dog, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 138755 Da |
| Gene ID | 490 |
|---|---|
| Other Names | Plasma membrane calcium-transporting ATPase 1, PMCA1, 3.6.3.8, Plasma membrane calcium ATPase isoform 1, Plasma membrane calcium pump isoform 1, ATP2B1, PMCA1 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ATP2B1 (aa312-327) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ATP2B1 |
|---|---|
| Synonyms | PMCA1 |
| Function | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Isoform B is ubiquitously expressed. Isoform C is found in brain cortex, skeletal muscle and heart muscle Isoform D has only been found in fetal skeletal muscle. Isoform K has been found in small intestine and liver |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize both reported isoforms (NP_001001323.1; NP_001673.2).
References
Insights into the oligomerization process of the C-terminal domain of human
plasma membrane Ca²+-ATPase. Benetti F, Mi?eti? I, Carsughi F, Spinozzi F, Bubacco L, Beltramini M. Arch Biochem Biophys. 2011 Feb 15;506(2):194-200. PMID: 21126504
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