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p15INK4b (isoform 2) Antibody (C-Term)

Peptide-affinity purified goat antibody

  • WB - p15INK4b (isoform 2) Antibody (C-Term) AF3669a
    AF3669a (1 µg/ml) staining of Human Gastrointestinal cancer lysate (35 µg protein in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P42772
Other Accession NP_004927.2, NP_511042.1, 1030
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 14722 Da
Additional Information
Gene ID 1030
Other Names Cyclin-dependent kinase 4 inhibitor B, Multiple tumor suppressor 2, MTS-2, p14-INK4b, p15-INK4b, p15INK4B, CDKN2B, MTS2
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautionsp15INK4b (isoform 2) Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MTS2
Function Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.
Cellular Location Cytoplasm. Note=Also found in the nucleus
Tissue Location Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines
Research Areas
Citations (0)

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This antibody is expected to recognize isoform 2 (NP_511042.1) only.


Strategies to re-express epigenetically silenced p15(INK4b) and p21(WAF1) genes in acute myeloid leukemia. Geyer CR. Epigenetics. 2010
Nov-Dec;5(8):696-703. Review. PMID: 21124069

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$ 325.00
Cat# AF3669a
(40 western blots)
Availability: 7-10 days
Bulk Size
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