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C16orf57 (aa154-167) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - C16orf57 (aa154-167) Antibody (internal region) AF3678a
    AF3678a (0.3 µg/ml) staining of Human Skin lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BQ65
Other Accession NP_078874.2, NP_001182231.1, 79650
Reactivity Human, Mouse, Rat
Predicted Pig
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 30268 Da
Additional Information
Gene ID 79650
Other Names U6 snRNA phosphodiesterase {ECO:0000255|HAMAP-Rule:MF_03040}, hUsb1, 3.1.4.- {ECO:0000255|HAMAP-Rule:MF_03040}, USB1 {ECO:0000255|HAMAP-Rule:MF_03040}, C16orf57
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsC16orf57 (aa154-167) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name USB1 {ECO:0000255|HAMAP-Rule:MF_03040}
Synonyms C16orf57
Function Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.
Cellular Location Nucleus {ECO:0000255|HAMAP-Rule:MF_03040, ECO:0000269|PubMed:22899009}
Research Areas
Citations (0)

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This antibody is expected to recognize both reported isoforms (NP_078874.2; NP_001182231.1).


Mutations in C16orf57 and normal-length telomeres unify a subset of patients with dyskeratosis congenita, poikiloderma with neutropenia and Rothmund-Thomson syndrome. Walne AJ, Vulliamy T, Beswick R, Kirwan M, Dokal I. Hum Mol Genet. 2010 Nov 15;19(22):4453-61. PMID: 20817924

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$ 325.00
Cat# AF3678a
(40 western blots)
Availability: 7-10 days
Bulk Size
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