|Other Accession||NP_006662.3, 6512, 242607 (mouse)|
|Predicted||Human, Mouse, Pig, Dog, Cow|
|Calculated MW||60658 Da|
|Other Names||Excitatory amino acid transporter 5, Retinal glutamate transporter, Solute carrier family 1 member 7, SLC1A7, EAAT5|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC1A7 (38-51) Antibody (internal region, near N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed primarily in retina. Detectable in liver, heart, muscle and brain|
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Provided below are standard protocols that you may find useful for product applications.
Regulation of the excitatory amino acid transporter EAAT5 by the serum
and glucocorticoid dependent kinases SGK1 and SGK3. Boehmer C, Rajamanickam J, Schniepp R, Kohler K, Wulff P, Kuhl D, Palmada M, Lang F. Biochem Biophys Res Commun. 2005 Apr 8;329(2):738-42. PMID: 15737648
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