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SLC6A4 (aa605-618) Antibody (C-Term)

Peptide-affinity purified goat antibody

  • WB - SLC6A4 (aa605-618) Antibody (C-Term) AF3701a
    AF3701a (0.5 µg/ml) staining of Mouse Small Intestine lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P31645
Other Accession NP_001036.1, 6532, 15567 (mouse), 25553 (rat)
Reactivity Mouse
Predicted Human, Rat, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 70325 Da
Additional Information
Gene ID 6532
Other Names Sodium-dependent serotonin transporter, 5HT transporter, 5HTT, Solute carrier family 6 member 4, SLC6A4, HTT, SERT
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLC6A4 (aa605-618) Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC6A4
Synonyms HTT, SERT
Function Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
Cellular Location Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Translocates from intracellular locations to the plasma membrane. Density of transporter molecules on the plasma membrane is itself regulated by serotonin
Tissue Location Expressed in platelets (at protein level).
Research Areas
Citations (0)

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Role of mother's genes and environment in postpartum depression. Mitchell C, Notterman D, Brooks-Gunn J, Hobcraft J, Garfinkel I, Jaeger K, Kotenko I, McLanahan S. Proc Natl Acad Sci U S A. 2011 May 17;108(20):8189-93. PMID: 21576482

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$ 325.00
Cat# AF3701a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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