|Application ||WB, E|
|Other Accession||NP_006400.2, NP_001177925.1, 10552, 56443 (mouse), 81824 (rat)|
|Predicted||Mouse, Rat, Pig, Cow|
|Calculated MW||41569 Da|
|Other Names||Actin-related protein 2/3 complex subunit 1A, SOP2-like protein, ARPC1A, SOP2L|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ARPC1A Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|
|Cellular Location||Cytoplasm, cytoskeleton.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_006400.2; NP_001177925.1). No cross-reactiviry expected with ARPC1B.
Characterization of the 7q21-q22 amplicon identifies ARPC1A, a subunit of the Arp2/3 complex, as a regulator of cell migration and invasion in pancreatic cancer. Laurila E, Savinainen K, Kuuselo R, Karhu R, Kallioniemi A. Genes Chromosomes Cancer. 2009 Apr;48(4):330-9. PMID: 19145645
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.