|Application ||WB, E|
|Other Accession||NP_006400.2, NP_001177925.1, 10552, 56443 (mouse), 81824 (rat)|
|Predicted||Mouse, Rat, Pig, Cow|
|Calculated MW||41569 Da|
|Other Names||Actin-related protein 2/3 complex subunit 1A, SOP2-like protein, ARPC1A, SOP2L|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ARPC1A Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|
|Cellular Location||Cytoplasm, cytoskeleton.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_006400.2; NP_001177925.1). No cross-reactiviry expected with ARPC1B.
Characterization of the 7q21-q22 amplicon identifies ARPC1A, a subunit of the Arp2/3 complex, as a regulator of cell migration and invasion in pancreatic cancer. Laurila E, Savinainen K, Kuuselo R, Karhu R, Kallioniemi A. Genes Chromosomes Cancer. 2009 Apr;48(4):330-9. PMID: 19145645
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