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CD128 / Cxcr2 (mouse) Antibody (N-Term)

Peptide-affinity purified goat antibody

     
  • WB - CD128 / Cxcr2 (mouse) Antibody (N-Term) AF3708a
    AF3708a (0.3 µg/ml) staining of Mouse Colon lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P25025
Other Accession NP_034039.1, 3579
Reactivity Mouse
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 40759 Da
Additional Information
Gene ID 3579
Other Names C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, CDw128b, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8R B, IL-8 receptor type 2, CD182, CXCR2, IL8RB
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD128 / Cxcr2 (mouse) Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CXCR2
Synonyms IL8RB
Function Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor (PubMed:1891716). Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G- protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:8662698). Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)
citation

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Background

Reported isoforms represent identical protein: NP_001548.1, NP_001161770.1. The immunizing peptide represent part of an extracellular domain.

References

CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion. Singh S, Nannuru KC, Sadanandam A, Varney ML, Singh RK, British journal of cancer 2009 May 100 (10): 1638-46. PMID: 19401689

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$ 341.00
Cat# AF3708a
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Availability: 7-10 days
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