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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   STRA8 (aa70-81) Antibody (internal region)   

STRA8 (aa70-81) Antibody (internal region)

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
E
Primary Accession Q7Z7C7
Other Accession NP_872295.1, 346673, 500079 (rat)
Predicted Human, Rat
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 36908 Da
Additional Information
Gene ID 346673
Other Names Stimulated by retinoic acid gene 8 protein homolog, STRA8 {ECO:0000312|EMBL:AAP47163.1}
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSTRA8 (aa70-81) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STRA8 {ECO:0000312|EMBL:AAP47163.1}
Function Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. Can associate with DNA (possibly in an indirect manner), and in vitro can activate DNA transcription (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P70278}. Nucleus {ECO:0000250|UniProtKB:P70278}. Note=Shuttles between nucleus and cytoplasm. Nuclear export is XPO1-dependent {ECO:0000250|UniProtKB:P70278}
Tissue Location Expressed specifically in testis and fetal ovaries.
Research Areas
Citations (0)

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References

Meiosis initiation in the human ovary requires intrinsic retinoic acid synthesis. Le Bouffant R, Guerquin MJ, Duquenne C, Frydman N, Coffigny H, Rouiller Fabre V, Frydman R, Habert R, Livera G. Hum Reprod. 2010 Oct;25(10):2579-90. PMID: 20670969

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$ 325.00
Cat# AF3776a
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