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LSM2 (aa33-46) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y333 |
| Other Accession | NP_067000.1, 57819, 27756 (mouse), 684148 (rat) |
| Reactivity | Human, Mouse |
| Predicted | Rat, Pig, Dog, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 10835 Da |
| Gene ID | 57819 |
|---|---|
| Other Names | U6 snRNA-associated Sm-like protein LSm2, Protein G7b, Small nuclear ribonuclear protein D homolog, snRNP core Sm-like protein Sm-x5, LSM2, C6orf28, G7B |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LSM2 (aa33-46) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LSM2 |
|---|---|
| Synonyms | C6orf28, G7B |
| Function | Plays a role in pre-mRNA splicing as component of the U4/U6- U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320). |
| Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
References
The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci. Ingelfinger D, Arndt-Jovin DJ, Lührmann R, Achsel T. RNA. 2002 Dec;8(12):1489-501. PMID: 12515382
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