|Other Accession||NP_945343.1, 341359, 54526 (mouse), 60567 (rat)|
|Predicted||Human, Mouse, Rat, Pig, Dog|
|Calculated MW||59127 Da|
|Other Names||Synaptotagmin-10, Synaptotagmin X, SytX, SYT10|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Synaptotagmin-10 Antibody (internal region, near C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein|
|Tissue Location||Expressed only in pancreas, lung and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X. Fukuda M, Kanno E, Mikoshiba K. J Biol Chem. 1999 Oct 29;274(44):31421-7. PMID: 10531343
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