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MAT2B (isoform 1) Antibody (N-Term)

Peptide-affinity purified goat antibody

     
  • WB - MAT2B (isoform 1) Antibody (N-Term) AF3803a
    AF3803a (0.3 µg/ml) staining of Human Thymus lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NZL9
Other Accession NP_037415.1, 27430, 108645 (mouse), 683630 (rat)
Reactivity Human
Predicted Mouse, Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 37552 Da
Additional Information
Gene ID 27430
Other Names Methionine adenosyltransferase 2 subunit beta, Methionine adenosyltransferase II beta, MAT II beta, Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase, MAT2B, TGR
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMAT2B (isoform 1) Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAT2B
Synonyms TGR
Function Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine (PubMed:10644686, PubMed:23189196, PubMed:25075345). Can bind NADP (in vitro) (PubMed:23189196, PubMed:23425511).
Tissue Location Widely expressed.
Research Areas
Citations (0)
citation

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Background

This antibody is expected to recognize reported isoform 1 (NP_037415.1) only.

References

Cloning, expression, and functional
characterization of the beta regulatory subunit of human methionine adenosyltransferase (MAT II). LeGros HL Jr, Halim AB, Geller AM, Kotb M. J Biol Chem. 2000 Jan 28;275(4):2359-66. PMID: 10644686

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$ 341.00
Cat# AF3803a
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Availability: 7-10 days
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