|Application ||WB, E|
|Other Accession||NP_037415.1, 27430, 108645 (mouse), 683630 (rat)|
|Predicted||Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||37552 Da|
|Other Names||Methionine adenosyltransferase 2 subunit beta, Methionine adenosyltransferase II beta, MAT II beta, Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase, MAT2B, TGR|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MAT2B (isoform 1) Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L- methionine (PubMed:10644686, PubMed:23189196, PubMed:25075345). Can bind NADP (in vitro) (PubMed:23189196, PubMed:23425511).|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize reported isoform 1 (NP_037415.1) only.
Cloning, expression, and functional
characterization of the beta regulatory subunit of human methionine adenosyltransferase (MAT II). LeGros HL Jr, Halim AB, Geller AM, Kotb M. J Biol Chem. 2000 Jan 28;275(4):2359-66. PMID: 10644686
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