Synaptotagmin-5 (aa 80-93) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | O00445 |
Other Accession | NP_058604.1, 6861, 53420 (mouse), 54309 (rat) |
Reactivity | Human |
Predicted | Mouse, Pig, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 42900 Da |
Gene ID | 6861 |
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Other Names | Synaptotagmin-5, Synaptotagmin V, SytV, SYT5 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Synaptotagmin-5 (aa 80-93) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SYT5 |
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Function | May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity). |
Cellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Recycling endosome membrane; Single-pass membrane protein. Note=In mast cells, localizes to the endocytic recycling compartment. |
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Provided below are standard protocols that you may find useful for product applications.
References
Identification of a nonneuronal isoform of synaptotagmin. Hudson AW, Birnbaum MJ. Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):5895-9. PMID: 7597049
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