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Caspase 12 (aa232-244) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6UXS9 |
| Other Accession | NP_001177945.1, 100506742 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 38907 Da |
| Gene ID | 100506742 |
|---|---|
| Other Names | Inactive caspase-12, CASP-12, CASP12 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Caspase 12 (aa232-244) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CASP12 |
|---|---|
| Function | May function as a negative regulator of inflammatory responses and innate immunity. May reduce cytokine release in response to bacterial lipopolysaccharide during infection. Reduces activation of NF-kappa-B in response to TNF (PubMed:15129283). May lack protease activity (Probable). |
| Tissue Location | Widely expressed, with highest levels in lung. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Purification of catalytically active caspase-12 and its biochemical characterization. Lee HJ, Lee SH, Park SH, Sharoar MG, Shin SY, Lee JS, Cho B, Park IS. Arch Biochem Biophys. 2010 Oct 1;502(1):68-73. PMID: 20646990
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