|Application ||WB, E|
|Other Accession||NP_001177945.1, 100506742|
|Calculated MW||38865 Da|
|Other Names||Inactive caspase-12, CASP-12, CASP12|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Caspase 12 (aa232-244) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF.|
|Tissue Location||Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis|
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Provided below are standard protocols that you may find useful for product applications.
Purification of catalytically active caspase-12 and its biochemical characterization. Lee HJ, Lee SH, Park SH, Sharoar MG, Shin SY, Lee JS, Cho B, Park IS. Arch Biochem Biophys. 2010 Oct 1;502(1):68-73. PMID: 20646990
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