|Application ||WB, E|
|Other Accession||NP_003557.2, 8411|
|Calculated MW||162466 Da|
|Other Names||Early endosome antigen 1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2, EEA1, ZFYVE2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EEA1 (aa821-835) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.|
|Cellular Location||Cytoplasm. Early endosome membrane; Peripheral membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1). Mishra A, Eathiraj S, Corvera S, Lambright DG. Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):10866-71. PMID: 20534488
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