|Application ||WB, IHC, E|
|Other Accession||NP_003017.1, 6456|
|Calculated MW||39962 Da|
|Other Names||Endophilin-A1, EEN-B1, Endophilin-1, SH3 domain protein 2A, SH3 domain-containing GRB2-like protein 2, SH3GL2, CNSA2, SH3D2A|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||endophilin-A1 / SH3GL2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein. Note=Concentrated in presynaptic nerve terminals in neurons|
|Tissue Location||Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum|
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SH3GL2 gene participates in MEK-ERK signal pathway partly by regulating EGFR in the laryngeal carcinoma cell line Hep2. Shang C, Guo Y, Fu S, Fu W, Sun K. Med Sci Monit. 2010 Jun;16(6):BR168-73. PMID: 20512084
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