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IL-17A (aa126-137) Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - IL-17A (aa126-137) Antibody (internal region) AF3853a
    AF3852a (1 µg/ml) staining of Human Lymph Node lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q16552
Other Accession NP_002181.1, 3605
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 17504 Da
Additional Information
Gene ID 3605
Other Names Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL17A, CTLA8, IL17
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL-17A (aa126-137) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL17A
Synonyms CTLA8, IL17
Function Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
Cellular Location Secreted.
Tissue Location Restricted to activated memory T-cells.
Research Areas
Citations (0)

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References

Epidermal CCR6+ ?? T cells are major producers of IL-22 and IL-17 in a murine model of psoriasiform dermatitis. Mabuchi T, Takekoshi T, Hwang ST. J Immunol. 2011 Nov 15;187(10):5026-31. PMID: 21984702

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$ 335.00
Cat# AF3853a
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