|Application ||WB, E|
|Other Accession||NP_000576.1, NP_751915.1, 3600|
|Calculated MW||18086 Da|
|Other Names||Interleukin-15, IL-15, IL15|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IL-15 (aa70-82) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.|
|Cellular Location||Isoform IL15-S48AA: Secreted.|
|Tissue Location||Most abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15- S21AA is preferentially expressed in tissues such as testis and thymus|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_000576.1; NP_751915.1).
B cell-derived IL-15 enhances CD8 T cell cytotoxicity and is increased in multiple sclerosis patients. Schneider R, Mohebiany AN, Ifergan I, Beauseigle D, Duquette P, Prat A, Arbour N. J Immunol. 2011 Oct 15;187(8):4119-28. PMID: 21911607
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