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Glycine receptor, alpha 1 (intracellular) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - Glycine receptor, alpha 1 (intracellular) Antibody (internal region) AF3877a
    AF3877a (0.3 µg/ml) staining of Mouse Testis lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23415
Other Accession NP_037265.1, 2741, 14654 (mouse), 25674 (rat)
Reactivity Mouse, Rat
Predicted Human, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 52624 Da
Additional Information
Gene ID 2741
Other Names Glycine receptor subunit alpha-1, Glycine receptor 48 kDa subunit, Glycine receptor strychnine-binding subunit, GLRA1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGlycine receptor, alpha 1 (intracellular) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GLRA1
Function The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
Cellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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The immunizing peptide represents part of the cytoplasmic domain. The antibody is not expected to cross-react with other glycine receptor alpha proteins.


Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor. Wang Q, Lynch JW. J Biol Chem. 2011 Nov 4;286(44):38814-24. PMID: 21917927

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$ 325.00
Cat# AF3877a
(40 western blots)
Availability: 7-10 days
Bulk Size
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