Glycine receptor, alpha 1 (intracellular) Antibody (internal region)
Peptide-affinity purified goat antibody
|Application ||WB, E|
|Other Accession||NP_037265.1, 2741, 14654 (mouse), 25674 (rat)|
|Predicted||Human, Pig, Dog, Cow|
|Calculated MW||52624 Da|
|Other Names||Glycine receptor subunit alpha-1, Glycine receptor 48 kDa subunit, Glycine receptor strychnine-binding subunit, GLRA1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Glycine receptor, alpha 1 (intracellular) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).|
|Cellular Location||Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The immunizing peptide represents part of the cytoplasmic domain. The antibody is not expected to cross-react with other glycine receptor alpha proteins.
Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor. Wang Q, Lynch JW. J Biol Chem. 2011 Nov 4;286(44):38814-24. PMID: 21917927
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.