|Application ||WB, E|
|Other Accession||NP_002300.1, 3976, 16878 (mouse), 60584 (rat)|
|Calculated MW||22008 Da|
|Other Names||Leukemia inhibitory factor, LIF, Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor, MLPLI, Emfilermin, LIF, HILDA|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LIF (aa28-39) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.|
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Leukemia inhibitory factor enhances endometrial stromal cell decidualization in humans and mice. Shuya LL, Menkhorst EM, Yap J, Li P, Lane N, Dimitriadis E. PLoS One. 2011;6(9):e25288. PMID: 21966484
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