Cd97 (mouse) Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9Z0M6 |
Other Accession | NP_036055.2, NP_001156501.1, NP_001156502.1, NP_001156503.1, 26364 |
Reactivity | Mouse |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 90413 Da |
Gene ID | 26364 |
---|---|
Other Names | CD97 antigen, CD97, Cd97 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Cd97 (mouse) Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Adgre5 {ECO:0000312|MGI:MGI:1347095} |
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Function | Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Although predominantly expressed by cells of the immune system, expressed ubiquitously with particularly high levels of expression in the lung and the thymus gland. In the spleen, expression is detected on most myeloid cells and variable portions of T-cells, B- cells and NK cells. In the bone marrow, expressed in nearly all myeloid cells, whereas little if any expression is found on erythroid cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize all reported isoforms (NP_036055.2; NP_001156501.1; NP_001156502.1; NP_001156503.1).
References
Deletion of either CD55 or CD97 ameliorates arthritis in mouse models. Hoek RM, de Launay D, Kop EN, Yilmaz-Elis AS, Lin F, Reedquist KA, Verbeek JS, Medof ME, Tak PP, Hamann J. Arthritis Rheum. 2010 Apr;62(4):1036-42. PMID: 20131275
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