|Application ||WB, E|
|Other Accession||NP_789847.1, NP_067643.3, NP_932159.1, 64236, 213019 (mouse), 290354 (rat)|
|Predicted||Human, Rat, Pig, Cow|
|Calculated MW||37459 Da|
|Other Names||PDZ and LIM domain protein 2, PDZ-LIM protein mystique, PDLIM2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PDLIM2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity.|
|Cellular Location||Cytoplasm. Nucleus. Note=May be partially nuclear Isoform 2: Cytoplasm, cytoskeleton.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize reported isoforms 1 and 2 (NP_789847.1; NP_067643.3).
Pdlim2 is a novel actin-regulating protein of podocyte foot processes. Sistani L, Dunér F, Udumala S, Hultenby K, Uhlen M, Betsholtz C, Tryggvason K, Wernerson A, Patrakka J. Kidney Int. 2011 Nov;80(10):1045-54. PMID: 21814175
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