|Application ||WB, E|
|Other Accession||NP_005808.3, NP_001157661.1, NP_001157666.1, 10226|
|Calculated MW||47075 Da|
|Other Names||Perilipin-3, 47 kDa mannose 6-phosphate receptor-binding protein, 47 kDa MPR-binding protein, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1, Placental protein 17, PP17, PLIN3, M6PRBP1, TIP47|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||perilipin 3 / TIP47 (aa154-167) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.|
|Cellular Location||Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lipid droplet Note=Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize all reported isoforms (NP_005808.3; NP_001157661.1; NP_001157666.1).
TIP47 protects mitochondrial membrane integrity and inhibits oxidative-stress-induced cell death. Hocsak E, Racz B, Szabo A, Mester L, Rapolti E, Pozsgai E, Javor S, Bellyei S, Gallyas F Jr, Sumegi B, Szigeti A. FEBS Lett. 2010 Jul 2;584(13):2953-60. PMID: 20556887
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