|Other Accession||NP_060741.3, NP_001231605.1, 55258|
|Predicted||Human, Dog, Cow|
|Calculated MW||54116 Da|
|Other Names||Threonine synthase-like 2, TSH2, 4.2.3.-, Secreted osteoclastogenic factor of activated T-cells, SOFAT, THNSL2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||THNSL2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Isoform 1: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho- threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity).|
|Cellular Location||Isoform SOFAT: Secreted. Note=Secreted by activated T-cells via a calcineurin-independent pathway|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize isoform 1 (NP_060741.3) and isoform 2 (NP_001231605.1) only.
A novel T cell cytokine, secreted osteoclastogenic factor of activated T cells, induces osteoclast formation in a RANKL-independent manner. Rifas L, Weitzmann MN. Arthritis Rheum. 2009 Nov;60(11):3324-35. PMID: 19877052
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