THNSL2 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | Q86YJ6 |
Other Accession | NP_060741.3, NP_001231605.1, 55258 |
Predicted | Human, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 54116 Da |
Gene ID | 55258 |
---|---|
Other Names | Threonine synthase-like 2, TSH2, 4.2.3.-, Secreted osteoclastogenic factor of activated T-cells, SOFAT, THNSL2 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | THNSL2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | THNSL2 |
---|---|
Function | [Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). |
Cellular Location | [Isoform SOFAT]: Secreted. Note=Secreted by activated T-cells via a calcineurin-independent pathway |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize isoform 1 (NP_060741.3) and isoform 2 (NP_001231605.1) only.
References
A novel T cell cytokine, secreted osteoclastogenic factor of activated T cells, induces osteoclast formation in a RANKL-independent manner. Rifas L, Weitzmann MN. Arthritis Rheum. 2009 Nov;60(11):3324-35. PMID: 19877052
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