|Application ||WB, E|
|Other Accession||NP_000587.1, 3484|
|Calculated MW||27904 Da|
|Other Names||Insulin-like growth factor-binding protein 1, IBP-1, IGF-binding protein 1, IGFBP-1, Placental protein 12, PP12, IGFBP1, IBP1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IGFBP1 (aa156-170) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.|
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Provided below are standard protocols that you may find useful for product applications.
IGFBP-1 is expressed specifically in ovarian clear cell adenocarcinoma. Sugita S, Morishita Y, Kano J, Furuya S, Shiba-Ishii A, Noguchi M. Histopathology. 2011 Apr;58(5):729-38. PMID: 21457161
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