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polo-like kinase 5 (aa309-322) Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - polo-like kinase 5 (aa309-322) Antibody (internal region) AF3961a
    AF3961a (2 µg/ml) staining of Cerebral Cortex ysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q496M5
Other Accession NP_001230008.1, 126520
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 36329 Da
Additional Information
Gene ID 126520
Other Names Inactive serine/threonine-protein kinase PLK5, Polo-like kinase 5, PLK-5, PLK5, PLK5P
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautionspolo-like kinase 5 (aa309-322) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLK5
Synonyms PLK5P
Function Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
Cellular Location Nucleus, nucleolus. Cytoplasm
Tissue Location Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in the liver, and some cells in the germinal center of lymph nodes (at protein level).
Research Areas
Citations (0)
citation

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References

Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression. de Cárcer G, Escobar B, Higuero AM, García L, Ansón A, Pérez G, Mollejo M, Manning G, Meléndez B, Abad-Rodríguez J, Malumbres M. Mol Cell Biol. 2011 Mar;31(6):1225-39. PMID: 21245385

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$ 341.00
Cat# AF3961a
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