|Application ||WB, E|
|Other Accession||NP_073626.1, NP_758525.1, 64806|
|Calculated MW||20330 Da|
|Other Names||Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, IL17E|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IL-25 / IL-17E (aa66-79) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.|
|Tissue Location||Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_073626.1; NP_758525.1).
T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma. Corrigan CJ, Wang W, Meng Q, Fang C, Wu H, Reay V, Lv Z, Fan Y, An Y, Wang YH, Liu YJ, Lee TH, Ying S. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1579-84. PMID: 21205894
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