|Application ||WB, E|
|Other Accession||NP_003273.1, NP_001139313.1, 7136|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||21339 Da|
|Other Names||Troponin I, fast skeletal muscle, Troponin I, fast-twitch isoform, TNNI2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TNNI2 (aa83-95) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_003273.1; NP_001139313.1). Reported variants represent identical protein: NP_001139301.1, NP_003273.1.
Expression of the fast twitch troponin complex, fTnT, fTnI and fTnC, in vascular smooth muscle. Moran CM, Garriock RJ, Miller MK, Heimark RL, Gregorio CC, Krieg PA. Cell Motil Cytoskeleton. 2008 Aug;65(8):652-61. PMID: 18548613
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