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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   Cone-rod homeobox (C Terminus) Antibody (internal region, near C-Term)   

Cone-rod homeobox (C Terminus) Antibody (internal region, near C-Term)

Peptide-affinity purified goat antibody

     
  • WB - Cone-rod homeobox (C Terminus) Antibody (internal region, near C-Term) AF4011a
    AF4011a (1 µg/ml) staining of Rat Retina lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O43186
Other Accession NP_000545.1, 1406, 12951 (mouse), 60446 (rat)
Reactivity Rat
Predicted Human, Mouse, Pig, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 32261 Da
Additional Information
Gene ID 1406
Other Names Cone-rod homeobox protein, CRX, CORD2
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCone-rod homeobox (C Terminus) Antibody (internal region, near C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRX
Synonyms CORD2
Function Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}
Tissue Location Retina.
Research Areas
Citations (0)

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References

Immunohistochemical expression of CRX in extracranial malignant small round cell tumors. Terry J, Calicchio ML, Rodriguez-Galindo C, Perez-Atayde AR. The American journal of surgical pathology 2012 Aug 36 (8): 1165-9. PMID: 22790857

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$ 335.00
Cat# AF4011a
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Availability: 7-10 days
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