|Application ||WB, E|
|Other Accession||NP_001248.1, NP_001207417.1, NP_001207418.1, NP_001207419.1, 1012, 12554 (mouse), 192248 (rat)|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||78287 Da|
|Other Names||Cadherin-13, Heart cadherin, H-cadherin, P105, Truncated cadherin, T-cad, T-cadherin, CDH13, CDHH|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CDH13 / H cadherin (aa285-297) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor.|
|Tissue Location||Highly expressed in heart. In the CNS, expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. No expression detected in cerebellum or spinal cord.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize isoform 1, 2, 3 and 4 (NP_001248.1; NP_001207417.1; NP_001207418.1; NP_001207419.1).
A variant upstream of the CDH13 adiponectin receptor gene and metabolic syndrome in Swedes. Fava C, Danese E, Montagnana M, Sjögren M, Almgren P, Guidi GC, Hedblad B, Engström G, Lechi A, Minuz P, Melander O. Am J Cardiol. 2011 Nov 15;108(10):1432-7. PMID: 21872196
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