|Application ||WB, E|
|Other Accession||NP_003217.3, 7033|
|Calculated MW||8641 Da|
|Other Names||Trefoil factor 3, Intestinal trefoil factor, hITF, Polypeptide P1.B, hP1.B, TFF3, ITF, TFI|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TFF3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).|
|Cellular Location||Secreted, extracellular space, extracellular matrix. Cytoplasm|
|Tissue Location||Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus. Also expressed in the hypothalamus where it is detected in paraventricular, periventricular and supraoptic nuclei (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Differential expression of gastric MUC5AC in colonic epithelial cells: TFF3-wired IL1 ?/Akt crosstalk-induced mucosal immune response against Shigella dysenteriae infection. Raja SB, Murali MR, Devaraj H, Devaraj SN. Journal of cell science 2012 Feb 125 (Pt 3): 703-13. PMID: 22389405
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