|Application ||WB, E|
|Other Accession||NP_004896.1, 9588|
|Calculated MW||25035 Da|
|Other Names||Peroxiredoxin-6, 18.104.22.168, 1-Cys peroxiredoxin, 1-Cys PRX, 24 kDa protein, Acidic calcium-independent phospholipase A2, aiPLA2, 3.1.1.-, Antioxidant protein 2, Liver 2D page spot 40, Non-selenium glutathione peroxidase, NSGPx, 22.214.171.124, Red blood cells page spot 12, PRDX6, AOP2, KIAA0106|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||peroxiredoxin 6 (aa170-180) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.|
|Cellular Location||Cytoplasm. Lysosome. Cytoplasmic vesicle. Note=Also found in lung secretory organelles.|
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Provided below are standard protocols that you may find useful for product applications.
Peroxiredoxin 6 interferes with TRAIL-induced death-inducing signaling complex formation by binding to death effector domain caspase. Choi H, Chang JW, Jung YK. Cell death and differentiation 2011 Mar 18 (3): 405-14. PMID: 20829884
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