|Other Accession||NP_006219.1, 5368|
|Calculated MW||20295 Da|
|Other Names||Prepronociceptin, Neuropeptide 1, Nociceptin, Orphanin FQ, PPNOC, Neuropeptide 2, PNOC, OFQ|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PNOC (aa27-38) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development (By similarity).|
|Tissue Location||Predominantly expressed in the brain and spinal cord. Also expressed and secreted by peripheral blood neutrophils following degranulation|
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Provided below are standard protocols that you may find useful for product applications.
Human neutrophils as a source of nociceptin: a novel link between pain and inflammation. Fiset ME, Gilbert C, Poubelle PE, Pouliot M. Biochemistry 2003 Sep 42 (35): 10498-505. PMID: 12950177
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