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>   home   >   Products   >   Primary Antibodies   >   Goat Anti-fibrinogen alpha chain Antibody   

Goat Anti-fibrinogen alpha chain Antibody

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02671
Other Accession NP_000499.1, NP_068657.1, 2243
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 94973 Da
Additional Information
Gene ID 2243
Other Names Fibrinogen alpha chain, Fibrinopeptide A, Fibrinogen alpha chain, FGA
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Immunogen Peptide with sequence C-STSYNRGDSTFES, from the internal region (near C terminus) of the protein sequence according to NP_000499.1; NP_068657.1.Please note the peptide is available for sale.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-fibrinogen alpha chain Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FGA
Function Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3- dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
Cellular Location Secreted.
Tissue Location Plasma.
Citations (0)

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This antibody is expected to recognize both reported isoforms (NP_000499.1; NP_068657.1).


Genetic variation in the fibrinogen-alpha and fibrinogen-gamma genes in relation to arterial stiffness: the Rotterdam Study. Sie MP, Isaacs A, de Maat MP, Mattace-Raso FU, Uitterlinden AG, Kardys I, Hofman A, Hoeks AP, Reneman RS, van Duijn CM, Witteman JC. Journal of hypertension 2009 Jul 27 (7): 1392-8. PMID: 19412134

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$ 325.00
Cat# AF4129a
(40 western blots)
Availability: 3-5 days
Bulk Size
Seasonal Special on Bulk Order
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