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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Goat Anti-ROR1 Antibody (C-Terminus (near))   

Goat Anti-ROR1 Antibody (C-Terminus (near))

Purified Goat Polyclonal Antibody

     
  • IHC-P - Goat Anti-ROR1 Antibody (C-Terminus (near)) AF4153a
    AF4153a (5 µg/ml) staining of paraffin embedded Human Breast cancer. Heated antigen retrieval with citrate buffer pH 6, DAB-staining.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC, E
Primary Accession Q01973
Other Accession 26563(mouse), 362550(rat), NP_005003.2
Reactivity Human
Predicted Human, Mouse, Rat
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 104283 Da
Additional Information
Gene ID 4919
Other Names ROR1; receptor tyrosine kinase-like orphan receptor 1; MGC99659; NTRKR1; dJ537F10.1; neurotrophic tyrosine kinase receptor-related 1
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence C-GNKSQKPYKIDSKQA, from the C-Terminus (near) of the protein sequence according to NP_005003.2.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-ROR1 Antibody (C-Terminus (near)) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ROR1
Synonyms NTRKR1
Function Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A- mediated signaling.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm
Research Areas
Citations (0)

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References

MiR-15a and miR-16-1 cluster functions in human leukemia. Calin GA, Cimmino A, Fabbri M, Ferracin M, Wojcik SE, Shimizu M, Taccioli C, Zanesi N, Garzon R, Aqeilan RI, Alder H, Volinia S, Rassenti L, Liu X, Liu CG, Kipps TJ, Negrini M, Croce CM. Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5166-71. Epub 2008 Mar 24.

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$ 335.00
Cat# AF4153a
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