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Goat Anti-CLEC12A / MICL Antibody (C Terminus)

Purified Goat Polyclonal Antibody

  • WB - Goat Anti-CLEC12A / MICL Antibody (C Terminus) AF4158a
    AF4158a (0.3 µg/ml) staining of U937 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5QGZ9
Other Accession NP_612210.4, NP_963917.2, NP_001193939.1
Reactivity Human
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 30762 Da
Additional Information
Gene ID 160364
Other Names CLEC12A; C-type lectin domain family 12, member A; CLL-1; CLL1; DCAL-2; MICL; C-type lectin domain family 12 member A; C-type lectin protein CLL-1; C-type lectin superfamily; C-type lectin-like molecule-1; dendritic cell-associated lectin 2; myeloid inhib
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence C-NPVQLGSTYFRE, from the C Terminus of the protein sequence according to NP_612210.4; NP_963917.2; NP_001193939.1.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-CLEC12A / MICL Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLEC12A
Synonyms CLL1, DCAL2, MICL
Function Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
Cellular Location Cell membrane; Single-pass type II membrane protein Note=Ligand binding leads to internalization
Tissue Location Detected in normal myeloid cells and in acute myeloid leukemia cells. Detected in neutrophils, eosinophils, monocytes and dendritic cells. Detected in spleen macrophage-rich red pulp and in lymph node (at protein level). Detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages
Research Areas
Citations (0)

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The C-type lectin Clec12A present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses. Lahoud MH, Proietto AI, Ahmet F, Kitsoulis S, Eidsmo L, Wu L, Sathe P, Pietersz S, Chang HW, Walker ID, Maraskovsky E, Braley H, Lew AM, Wright MD, Heath WR, Shortman K, Caminschi I. Journal of immunology (Baltimore, Md. : 1950) 2009 Jun 182 (12): 7587-94.

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$ 325.00
Cat# AF4158a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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