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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Goat Anti-CD47 Antibody (internal region (near C terminus))   

Goat Anti-CD47 Antibody (internal region (near C terminus))

Purified Goat Polyclonal Antibody

  • WB - Goat Anti-CD47 Antibody (internal region (near C terminus)) AF4164a
    AF4164a (0.3 µg/ml) staining of Human Hippocampus (A) and HeLa (B) lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q08722
Other Accession NP_001768.1, NP_942088.1
Reactivity Human
Predicted Human, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 35214 Da
Additional Information
Gene ID 961
Other Names CD47; CD47 molecule; IAP; MER6; OA3; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 glycoprotein; Rh-related antigen; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; integrin associ
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence C-SNQKTIQPPRK, from the internal region (near C terminus) of the protein sequence according to NP_001768.1; NP_942088.1.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-CD47 Antibody (internal region (near C terminus)) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD47
Synonyms MER6
Function Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain
Research Areas
Citations (0)

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Endothelial CD47 promotes vascular endothelial-cadherin tyrosine phosphorylation and participates in T cell recruitment at sites of inflammation in vivo. Azcutia V, Stefanidakis M, Tsuboi N, Mayadas T, Croce KJ, Fukuda D, Aikawa M, Newton G, Luscinskas FW. Journal of immunology (Baltimore, Md. : 1950) 2012 Sep 189 (5): 2553-62.

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$ 325.00
Cat# AF4164a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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