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Goat Anti-SCARB1 / SR-BI Antibody (C Terminus)

Purified Goat Polyclonal Antibody

  • WB - Goat Anti-SCARB1 / SR-BI Antibody (C Terminus) AF4167a
    AF4167a (0.01 µg/ml) staining of Human Adrenal Gland lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WTV0
Other Accession NP_005496.4
Reactivity Human
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 60878 Da
Additional Information
Gene ID 949
Other Names SCARB1; scavenger receptor class B, member 1; CD36L1; CLA-1; CLA1; HDLQTL6; SR-BI; SRB1; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; scavenger receptor class B member 1; scavenger receptor class B type III
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence C-TSAPKGSVLQEAK, from the C Terminus of the protein sequence according to NP_005496.4.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-SCARB1 / SR-BI Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CD36L1, CLA1
Function Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein. Note=Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae
Tissue Location Widely expressed.
Research Areas
Citations (0)

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An involvement of SR-B1 mediated PI3K-Akt-eNOS signaling in HDL-induced cyclooxygenase 2 expression and prostacyclin production in endothelial cells. Zhang QH, Zu XY, Cao RX, Liu JH, Mo ZC, Zeng Y, Li YB, Xiong SL, Liu X, Liao DF, Yi GH. Biochem Biophys Res Commun. 2012 Mar 30;420(1):17-23.

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$ 325.00
Cat# AF4167a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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