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Goat Anti-LCP1 / plastin-2 Antibody (internal region)

Purified Goat Polyclonal Antibody

  • WB - Goat Anti-LCP1 / plastin-2 Antibody (internal region) AF4178a
    AF4178a (0.5 µg/ml) staining of Daudi (A) and U937 (B) lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13796
Other Accession NP_002289.2
Reactivity Human
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 70288 Da
Additional Information
Gene ID 3936
Other Names LCP1; CP64; DKFZp781A23186; FLJ25423; FLJ26114; FLJ39956; L-PLASTIN; LC64P; LPL; PLS2; lymphocyte cytosolic protein 1 (L-plastin); L-plastin; L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P); Lymphocyte cytosolic protein-1 (plasmin); OTTHUMP00000018362; bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)); plastin 2
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence HLENAGCNKIGNFST, from the internal region of the protein sequence according to NP_002289.2.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-LCP1 / plastin-2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LCP1
Synonyms PLS2
Function Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69.
Cellular Location Cytoplasm, cytoskeleton. Cell junction. Cell projection. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28. Associated with the actin cytoskeleton at membrane ruffles (By similarity). Relocalizes to actin-rich cell projections upon serine phosphorylation.
Tissue Location Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T- lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.
Research Areas
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Composite three-marker assay for early detection of kidney cancer. Su Kim D, Choi YD, Moon M, Kang S, Lim JB, Kim KM, Park KM, Cho NH.Su Kim D, Choi YD, Moon M, Kang S, Lim JB, Kim KM, Park KM, Cho NH.Su Kim D, Choi YD, Moon M, Kang S, Lim JB, Kim KM, Park KM, Cho NH. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2013 Mar 22 (3): 390-8.

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$ 325.00
Cat# AF4178a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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