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Goat Anti-SERPINF1 / PEDF Antibody (internal region)

Purified Goat Polyclonal Antibody

     
  • WB - Goat Anti-SERPINF1 / PEDF Antibody (internal region) AF4180a
    AF4180a (0.3 µg/ml) staining of Human Albumin-depleted Plasma (A) and Serum (B) lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P36955
Other Accession NP_002606.3
Reactivity Human
Predicted Human, Pig, Cow, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 46312 Da
Additional Information
Gene ID 5176
Other Names SERPINF1; EPC-1; PEDF; PIG35; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; pigment epithelium-derived factor; proliferation-inducing protein 35; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence C-KITGKPIKLTQVEHR, from the internal region of the protein sequence according to NP_002606.3.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-SERPINF1 / PEDF Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SERPINF1
Synonyms PEDF
Function Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Cellular Location Secreted. Melanosome. Note=Enriched in stage I melanosomes
Tissue Location Retinal pigment epithelial cells and blood plasma.
Research Areas
Citations (0)

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References

pposing effects of pigment epithelium-derived factor on breast cancer cell versus neuronal survival: implication for brain metastasis and metastasis-induced brain damage. Fitzgerald DP et al. Cancer Res. 2012 Jan 1;72(1):144-53.

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$ 335.00
Cat# AF4180a
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