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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Goat Anti-CD74 Antibody (internal region)   

Goat Anti-CD74 Antibody (internal region)

Purified Goat Polyclonal Antibody

  • WB - Goat Anti-CD74 Antibody (internal region) AF4182a
    AF4182a (0.01 µg/ml) staining of Human Tonsil lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04233
Other Accession NP_001020330.1, NP_004346.1
Reactivity Human
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 33516 Da
Additional Information
Gene ID 972
Other Names CD74; DHLAG; HLADG; Ia-GAMMA; CD74 molecule, major histocompatibility complex, class II invariant chain; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); HLA-DR-gamma; Ia-associated invariant chain; MHC HLA-DR gamma chain; gamma chain of class II antigens
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence C-KGSFPENLRHLKN, from the internal region of the protein sequence according to NP_001020330.1; NP_004346.1.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-CD74 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD74
Synonyms DHLAG
Function Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Cellular Location Cell membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane. Golgi apparatus, trans-Golgi network. Endosome Lysosome. Note=Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane
Research Areas
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CD74: a potential novel target for triple-negative breast cancer. Tian B, Zhang Y, Li N, Liu X, Dong J. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2012 Dec 33 (6): 2273-7.

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$ 325.00
Cat# AF4182a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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