|Application ||WB, E|
|Other Accession||NP_932170.1, NP_000725.1|
|Calculated MW||18696 Da|
|Other Names||CD247; CD247 molecule; CD3-ZETA; CD3H; CD3Q; CD3Z; T3Z; TCRZ; CD247 antigen, zeta subunit; CD3Z antigen, zeta polypeptide (TiT3 complex); CD3zeta chain; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor T3 zeta chain; T-cell surface glycoprotein CD3 zeta chain; TCR zeta chain|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-KNPQEGLYNELQKD, from the internal region of the protein sequence according to NP_932170.1; NP_000725.1.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-CD3-ZETA / CD247 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD3Z, T3Z, TCRZ|
|Function||Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Association of CD247 polymorphisms with rheumatoid arthritis: a replication study and a meta-analysis. Teruel M, McKinney C, Balsa A, Pascual-Salcedo D, Rodriguez-Rodriguez L, Ortiz AM, Gómez-Vaquero C, González-Gay MA, Smith M, Witte T, Merriman T, Lie BA, Martin J. PloS one 2013 8 (7): e68295.
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