|Calculated MW||54986 Da|
|Other Names||CD3EAP; CD3e molecule, epsilon associated protein; ASE-1; ASE1; CAST; PAF49; A34.5; CD3 epsilon associated protein; CD3-epsilon-associated protein; CD3E-associated protein; CD3e antigen, epsilon polypeptide associated protein; DNA-directed RNA polymerase I subunit RPA34; RNA polymerase I-associated factor PAF49; antisense to ERCC 1; antisense to ERCC-1 protein|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-PEDKTVKQEQINTEP, from the internal region of the protein sequence according to NP_036231.1.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-CD3EAP Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ASE1, CAST, PAF49|
|Function||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation.|
|Cellular Location||Nucleus, nucleolus. Chromosome. Note=Found at the fibrillar centers of the nucleolus in interphase and during cell division it is localized to the nucleolus organizer regions of the chromosomes|
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Effects of PPP1R13L and CD3EAP variants on lung cancer susceptibility among nonsmoking Chinese women. Yin J, Guo L, Wang C, Wang H, Ma Y, Liu J, Liang D, Ma J, Zhao Y. Gene 2013 Jul 524 (2): 228-31.
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