|Application ||WB, E|
|Calculated MW||130848 Da|
|Other Names||ITGA1; integrin, alpha 1; CD49a; VLA1; CD49 antigen-like family member A; VLA-1; integrin alpha-1; laminin and collagen receptor; very late activation protein 1|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-DKHDFQDSVRIT, from the internal region of the protein sequence according to NP_852478.1.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-ITGA1 / VLA1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Integrin alpha1beta1 (VLA-1) mediates adhesion of activated intraepithelial lymphocytes to collagen. Roberts AI, Brolin RE, Ebert EC. Immunology 1999 Aug 97 (4): 679-85.
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