|Application ||WB, E|
|Other Accession||22352(mouse), 81818(rat), NP_003371.2|
|Predicted||Human, Mouse, Rat, Pig, Cow, Dog|
|Calculated MW||53652 Da|
|Other Names||VIM; vimentin; FLJ36605|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-QVINETSQHHDDLE, from the C Terminus of the protein sequence according to NP_003371.2.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Vimentin Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.|
|Tissue Location||Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone- independent mammary carcinoma cell lines|
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Diagnostic value of anti-modified citrullinated vimentin in rheumatoid arthritis. Maraina CH, Nurdayana AK, Rusni D, Azwany Y. Int J Rheum Dis. 2010 Oct;13(4):335-9.
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