|Application ||IHC, E|
|Other Accession||330260(mouse), 296851(rat), NP_000296.2, NP_001018171.1|
|Predicted||Human, Mouse, Rat, Pig, Cow, Dog|
|Calculated MW||39397 Da|
|Other Names||PON2; paraoxonase 2; A-esterase 2; aromatic esterase 2; paraoxonase nirs; serum aryldialkylphosphatase 2; serum paraoxonase/arylesterase 2|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-ERLLALRNRLKAS, from the internal region of the protein sequence according to NP_000296.2; NP_001018171.1.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-PON2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.|
|Cellular Location||Membrane; Peripheral membrane protein|
|Tissue Location||Widely expressed with highest expression in liver, lung, placenta, testis and heart|
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Paraoxonase gene polymorphism in south-western Korean population. Shin BS, Journal of Korean medical science 2009 Aug 24 (4): 561-6.
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