Goat Anti-FCRL2 Antibody (internal region)
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q96LA5 |
Other Accession | NP_110391.2 |
Reactivity | Human |
Predicted | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 |
Calculated MW | 55542 Da |
Gene ID | 79368 |
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Other Names | FCRL2; Fc receptor-like 2; CD307b; FCRH2; IFGP4; IRTA4; SPAP1; SPAP1A; SPAP1B; SPAP1C; Fc receptor-like protein 2; IFGP family protein 4; SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1; fc receptor h |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Immunogen | Peptide with sequence C-DKTSNIVKIKVQE, from the internal region of the protein sequence according to NP_110391.2. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-FCRL2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FCRL2 |
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Synonyms | FCRH2, IFGP4, IRTA4, SPAP1 |
Function | May have an regulatory role in normal and neoplastic B cell development. |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B-cell lines Preferentially expressed in memory B-cells (at protein level) |
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Provided below are standard protocols that you may find useful for product applications.
References
FcR-like 2 Inhibition of B cell receptor-mediated activation of B cells. Jackson TA, Haga CL, Ehrhardt GR, Davis RS, Cooper MD. Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 185 (12): 7405-12.
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