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Goat Anti-BOD1L Antibody (C Terminus)
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q8NFC6 |
| Other Accession | 665775(mouse), NP_683692.2 |
| Predicted | Human, Cow, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 |
| Calculated MW | 330466 Da |
| Gene ID | 259282 |
|---|---|
| Other Names | Bod1L; biorientation of chromosomes in cell division 1-like; FAM44A; KIAA1327; family with sequence similarity 44, member A |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | Peptide with sequence C-RTRGQQRVEEAP, from the C Terminus of the protein sequence according to NP_683692.2. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-BOD1L Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BOD1L1 (HGNC:31792) |
|---|---|
| Function | Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2- dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBH1 and BLM (PubMed:26166705, PubMed:29937342). Does not regulate spindle orientation (PubMed:26166705). |
| Cellular Location | Chromosome {ECO:0000269|Ref.2}. Note=Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection. {ECO:0000269|Ref.2} |
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Application Protocols
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References
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$ 216.00
Cat# AF4241a
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